Publications
2026
Kim S, Kim YJ, Kim N, Kim U, Park YS, Yun JH, Heo J, Lee H, Choi J, Park S, Jeong I, Kim BJ*, Shin HY*, SAMM50 rs3761472 causes mitochondrial dysfunction and progression of metabolic dysfunction-associated steatotic liver disease, Molecular Metabolism, 2026, 111:102423 (IF 6.3, JCR Top 15%)
Kim N, Kim S, Lee TE, Oh DK, Shin HY, 10-epi-PDX alleviates high-fat-diet-induced obesity by modulating lipid droplet dynamics and restoring metabolic balance, Biomedicine & Pharmacotherapy, 2026, 200:119531 (IF 7.5, JCR Top 5%)
Kim S, Kim U, Kim N, Lee TE, Lee J, Oh DK, Shin HY, 10-epi-Protectin DX and Resolvin D5n-3 DPA Attenuate Multi-Organ Inflammatory Injury in an LPS-Induced Murine Endotoxemia Model, Int J Mol Sci, 2026, 27:3356
Kim S, Kim N, Kim U, Lee J, Lee H, Chio J, Heo J, Oh D-K, Shin HY, Resolvin D5n-3 DPA protects against lung injury by modulating the NLRP3 inflammasome and immune pathways, Biomedicine & Pharmacotherapy, 2026, 198:119253 (IF 7.5, JCR Top 5%)
2024
2021
Kwon S, Shin HY, Advanced CRISPR-Cas Effector Enzyme-Based Diagnostics for Infectious Diseases, Including COVID-19, Life, 2021, 11:1356
Choi H, Chun J, Park M, Kim S, Kim N, Lee HJ, Kim M, Shin HY, Oh YK, Kim YB, The Safe Baculovirus-Based PrM/E DNA Vaccine Protected Fetuses Against Zika Virus in A129 Mice, Vaccines, 2021, 9:438
Cho H, Jang Y, Park KH, Choi H, Nowakowska A, Lee HJ, Kim M, Kang MH, Kim JH, Shin HY, Oh YK, Kim YB, Human endogenous retrovirus-enveloped baculoviral DNA vaccines against MERS-CoV and SARS-CoV2, NPJ Vaccines, 2021, 6:37
Petrenko O, Li J, Cimica V, Mena-Taboada P, Shin HY, D'Amico S, Reich NC, IL-6 promotes MYC-induced B cell lymphomagenesis independent of STAT3, PLoS One, 2021, 163:e0247394
2020
Kim U, Kim N, Shin HY, Modeling Non-Alcoholic Fatty Liver Disease (NAFLD) Using "Good-Fit" Genome-Editing Tools, Cells, 2020, 9:2572
Shin HY, Choi H, Kim N, Park N, Kim H, Kim J, Kim YB, Unraveling the Genome-Wide Impact of Recombinant Baculovirus Infection in Mammalian Cells for Gene Delivery, Genes (Basel), 2020, 11:1306
2019
Bae SE, Kim SS, Moon ST, Cho YD, Lee HS, Lee JY, Shin HY, Lee HJ*, Kim YB*, Construction of the safe neutralizing assay system using pseudotyped Nipah virus and G protein-specific monoclonal antibody, Biochemical and Biophysical Research Communications, 2019, 513:781-786
2018
Heo JH, Heo Y, Lee HJ, Kim M, Shin HY, Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis, BMC Complementary & Alternative Medicine, 2018, 18: 331 (JCR Top 30%)
Shin HY, The structural and functional roles of CTCF in the regulation of cell type-specific and human disease-associated super-enhancers, Genes & Genomics, 2018, 41:257-265
Shin HY, Hennighausen L, Yoo KH, STAT5-Driven Enhancers Tightly Control Temporal Expression of Mammary-Specific Genes, Journal of Mammary Gland Biology and Neoplasia, 2018, 24:61-71
Yoo KH, Hennighausen L, Shin HY, Dissecting Tissue-Specific Super-Enhancers by Integrating Genome-Wide Analyses and CRISPR/Cas9 Genome Editing, Journal of Mammary Gland Biology and Neoplasia, 2018, 24:47-59
Lee HK, Willi M, Shin HY, Liu C, Hennighausen L, Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation, Nucleic Acids Research, 2018, 46: 10796-10809 (IF 11.561, JCR Top 4%)
Shin HY, Targeting super-enhancers for disease treatment and diagnosis, Molecules and Cells, 2018, 41:506-514 (IF 3.077)
2017
Shin HY*(First & co-corresponding), Wang C*, Lee HK*, Yoo KH, Zeng X, Kuhn T, Yang CM, Mohr T, Liu C, Hennighausen L, CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome, Nature Communications, 2017, 8:15464 (IF 12.353, JCR Top 4%)
2016
Zeng X, Willi M, Shin HY, Hennighausen L and Wang C, Lineage-specific and non-specific cytokine-sensing genes respond differentially to the master regulator STAT5, Cell Reports, 2016, 17:3333-3346 (IF 8.032, JCR Top 15%)
Shin HY*, Willi M*, Yoo KH*, Zeng X, Wang C, Metser G, Hennighausen L, Hierarchy within the mammary STAT5-driven Wap super-enhancer, Nature Genetics, 2016, 48:904-11 (IF 27.125, JCR Top 1%)
Sakamoto K, Wehde BL, Yoo KH, Kim T, Rajbhandari N, Shin HY, Triplett AA, R？dler PD, Schuler F, Villunger A, Kang K, Hennighausen L, Wagner KU, Janus Kinase 1 is essential for inflammatory cytokine signaling and mammary gland remodeling, Molecular and Cellular Biology, 2016, 36:1673-90 (IF 3.813)
Metser G*, Shin HY*(co-first), Wang C, Yoo KH, Oh S, Villarino A, O’shea J, Kang K, Hennighausen L, An autoregulatory enhancer controls mammary-specific STAT5 functions, Nucleic Acids Research, 2016, 44:1052-1063 (IF 11.561, JCR Top 4%)
2013
Shin HY, Reich NC, Dynamic Trafficking of STAT5 Depends on an Unconventional Nuclear Localization Signal, Journal of Cell Science, 2013, 126:3333-3343 (IF 4.431)
2003
Kim E, Kim JH, Shin HY, Lee H, Yang JM, Kim J, Sohn JH, Kim H, Yun CO, Ad-mTERT-19, a Conditional Replication-Competent Adenovirus Driven by the Human Telomerase Promoter, Selectively Replicates in and Elicits Cytopathic Effect in a Cancer Cell-Specific Manner, Human Gene Therapy, 2003, 14:1415-1428 (IF 4.241, JCR Top 20%)
Kim E, Kim JH, Shin HY, Lee HS, Sohn JH, Yang JM, Kim J, Yun CO, Development of a Conditional Replication Competent Adenovirus, Controlled by the Human Telomerase Promoter (hTERT), Cancer Research and Treatment, 2003, 35:191-206
2023
Lee M, Seok J, Saha SK, Cho S, Jeong Y, Gil M, Kim A, Shin HY, Bae H, Do JT, Kim YB, Cho SG, Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers, Int J Stem Cells, 2023, 16:215
2022
Jang Y, Cho H, Chun J, Park K, Nowakowska A, Kim J, Lee H, Lee C, Han Y, Lee HJ, Shin HY, Kim YB, Baculoviral COVID-19 Delta DNA vaccine cross-protects against SARS-CoV2 variants in K18-ACE2 transgenic mice, Vaccine, 2022, 41:1223
Kim U, Kim S, Kim N, Shin HY, Mammary-Enriched Transcription Factors Synergize to Activate the Wap Super-Enhancer for Mammary Gland Development, Int J Mol Sci, 2022, 23:11680
Kim S, Shin HY, Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases, Int J Mol Sci, 2022, 23:11297
Kim S, Shin HY, Understanding the Tissue Specificity of ZIKV Infection in Various Animal Models for Vaccine Development, Vaccines, 2022, 10:1517
Kim S, Nowakowska A, Kim YB, Shin HY, Integrated CRISPR-Cas9 System-Mediated Knockout of IFN-γ and IFN-γ Receptor 1 in the Vero Cell Line Promotes Viral Susceptibility, Int J Mol Sci, 2022, 23:8217
Choi MK, Kim J, Park HM, Lim CM, Pham TH, Shin HY, Kim SE, Oh DK, Yoon DY, The DPA-derivative 11S, 17S-dihydroxy 7,9,13,15,19 (Z,E,Z,E,Z)-docosapentaenoic acid inhibits IL-6 production by inhibiting ROS production and ERK/NF-κB pathway in keratinocytes HaCaT stimulated with a fine dust PM10, Ecotoxicol Environ Saf, 2022, 232:113252
Kim N, Shin HY, Deciphering the Potential Role of Specialized Pro-Resolving Mediators in Obesity-Associated Metabolic Disorders, Int J Mol Sci, 2024, 25:9598
Kim N, Choi H, Kim U, Kim S, Kim YB*, Shin HY*, Sustained Microglial Activation Promotes Synaptic Loss and Neuronal Dysfunction after Recovery from ZIKV, Int J Mol Sci, 2024, 25:9451
Kim U, Kim DH, Oh DK, Shin HY*, Lee CH*, Gene Expression and Metabolome Analysis Reveals Anti-Inflammatory Impacts of 11,17diHDoPE on PM10-Induced Mouse Lung Inflammation, Int J Mol Sci, 2024, 25:5360
Kim NY, Park HM, Park JY, Kim U, Shin HY, Lee HP, Hong JT, Yoon DY, MMPP is a novel VEGFR2 inhibitor that suppresses angiogenesis via VEGFR2/AKT/ERK/NF-κB pathway, BMB rep, 2024, 57-244