Publications
2022
2021
Kwon S, Shin HY, Advanced CRISPR-Cas Effector Enzyme-Based Diagnostics for Infectious Diseases, Including COVID-19, Life, 2021, 11:1356
Choi H, Chun J, Park M, Kim S, Kim N, Lee HJ, Kim M, Shin HY, Oh YK, Kim YB, The Safe Baculovirus-Based PrM/E DNA Vaccine Protected Fetuses Against Zika Virus in A129 Mice, Vaccines, 2021, 9:438
Cho H, Jang Y, Park KH, Choi H, Nowakowska A, Lee HJ, Kim M, Kang MH, Kim JH, Shin HY, Oh YK, Kim YB, Human endogenous retrovirus-enveloped baculoviral DNA vaccines against MERS-CoV and SARS-CoV2, NPJ Vaccines, 2021, 6:37
Petrenko O, Li J, Cimica V, Mena-Taboada P, Shin HY, D'Amico S, Reich NC, IL-6 promotes MYC-induced B cell lymphomagenesis independent of STAT3, PLoS One, 2021, 163:e0247394
2020
Kim U, Kim N, Shin HY, Modeling Non-Alcoholic Fatty Liver Disease (NAFLD) Using "Good-Fit" Genome-Editing Tools, Cells, 2020, 9:2572
Shin HY, Choi H, Kim N, Park N, Kim H, Kim J, Kim YB, Unraveling the Genome-Wide Impact of Recombinant Baculovirus Infection in Mammalian Cells for Gene Delivery, Genes (Basel), 2020, 11:1306
2019
Bae SE, Kim SS, Moon ST, Cho YD, Lee HS, Lee JY, Shin HY, Lee HJ*, Kim YB*, Construction of the safe neutralizing assay system using pseudotyped Nipah virus and G protein-specific monoclonal antibody, Biochemical and Biophysical Research Communications, 2019, 513:781-786
2018
Heo JH, Heo Y, Lee HJ, Kim M, Shin HY, Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis, BMC Complementary & Alternative Medicine, 2018, 18: 331 (JCR Top 30%)
Shin HY, The structural and functional roles of CTCF in the regulation of cell type-specific and human disease-associated super-enhancers, Genes & Genomics, 2018, 41:257-265
Shin HY, Hennighausen L, Yoo KH, STAT5-Driven Enhancers Tightly Control Temporal Expression of Mammary-Specific Genes, Journal of Mammary Gland Biology and Neoplasia, 2018, 24:61-71
Yoo KH, Hennighausen L, Shin HY, Dissecting Tissue-Specific Super-Enhancers by Integrating Genome-Wide Analyses and CRISPR/Cas9 Genome Editing, Journal of Mammary Gland Biology and Neoplasia, 2018, 24:47-59
Lee HK, Willi M, Shin HY, Liu C, Hennighausen L, Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation, Nucleic Acids Research, 2018, 46: 10796-10809 (IF 11.561, JCR Top 4%)
Shin HY, Targeting super-enhancers for disease treatment and diagnosis, Molecules and Cells, 2018, 41:506-514 (IF 3.077)
2017
Shin HY*(First & co-corresponding), Wang C*, Lee HK*, Yoo KH, Zeng X, Kuhn T, Yang CM, Mohr T, Liu C, Hennighausen L, CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome, Nature Communications, 2017, 8:15464 (IF 12.353, JCR Top 4%)
2016
Zeng X, Willi M, Shin HY, Hennighausen L and Wang C, Lineage-specific and non-specific cytokine-sensing genes respond differentially to the master regulator STAT5, Cell Reports, 2016, 17:3333-3346 (IF 8.032, JCR Top 15%)
Shin HY*, Willi M*, Yoo KH*, Zeng X, Wang C, Metser G, Hennighausen L, Hierarchy within the mammary STAT5-driven Wap super-enhancer, Nature Genetics, 2016, 48:904-11 (IF 27.125, JCR Top 1%)
Sakamoto K, Wehde BL, Yoo KH, Kim T, Rajbhandari N, Shin HY, Triplett AA, R？dler PD, Schuler F, Villunger A, Kang K, Hennighausen L, Wagner KU, Janus Kinase 1 is essential for inflammatory cytokine signaling and mammary gland remodeling, Molecular and Cellular Biology, 2016, 36:1673-90 (IF 3.813)
Metser G*, Shin HY*(co-first), Wang C, Yoo KH, Oh S, Villarino A, O’shea J, Kang K, Hennighausen L, An autoregulatory enhancer controls mammary-specific STAT5 functions, Nucleic Acids Research, 2016, 44:1052-1063 (IF 11.561, JCR Top 4%)
2013
Shin HY, Reich NC, Dynamic Trafficking of STAT5 Depends on an Unconventional Nuclear Localization Signal, Journal of Cell Science, 2013, 126:3333-3343 (IF 4.431)
2003
Kim E, Kim JH, Shin HY, Lee H, Yang JM, Kim J, Sohn JH, Kim H, Yun CO, Ad-mTERT-19, a Conditional Replication-Competent Adenovirus Driven by the Human Telomerase Promoter, Selectively Replicates in and Elicits Cytopathic Effect in a Cancer Cell-Specific Manner, Human Gene Therapy, 2003, 14:1415-1428 (IF 4.241, JCR Top 20%)
Kim E, Kim JH, Shin HY, Lee HS, Sohn JH, Yang JM, Kim J, Yun CO, Development of a Conditional Replication Competent Adenovirus, Controlled by the Human Telomerase Promoter (hTERT), Cancer Research and Treatment, 2003, 35:191-206
Shin HY, Gene Therapy using CRISPR/Cas9 Technologies, The Korean Society for AIDS, Seoul, Korea, 2019 (oral presentation)
Kwon S*, Kim U*, Shin HY, Progressive Establishment of Mammary-Specific Super-Enhancers, Cell Symposia: Transcriptional Regulation in Evolution, Development, and Disease, Chicago, IL, USA, 2019
Shin HY, Dynamic Chromatin Remodeling of Cell-Type Specific Super-Enhancers, Cell Cycle Symposium, Korean Society for Molecular and Cellular Biology, Samcheok, Korea, 2019 (oral presentation)
Shin HY, Oh S, Yoo KH, Metser G, Hennighausen, Mammary-specific high-definition enhancers: How to induce genes 10,000-fold during pregnancy, NIH Research Festival, Bethesda, MD, 2015
Shin HY, Yoo KH, Metser G, Oh S, Hennighausen L, Activation of the mammary transcriptome during pregnancy, Gordon Research Conference, Westdover, Vermont, 2015
Metser G, Oh S, Shin HY, Wang C, Hennighausen L, Mammary-specific autoregulation of Stat5 genes ensures epithelial cell differentiation during pregnancy, Gordon Research Conference, Westdover, Vermont, 2015
Shin HY, Reich NC, Dynamic Trafficking of STAT5 Depends on an Unconventional Nuclear Localization Signal, International Cytokine and Interferon Society, San Francisco, California, 2013 (research abstract selected for an oral presentation)
Shin HY, Iyer J, Reich NC, STAT5a Nuclear Trafficking, Annual Conference of Society for Leukocyte Biology, International Cytokine Society, and International Society for Interferon and Cytokine Research, 2009 (Milstein Travel Award), Lisbon, Portugal
Shin HY, Yang JM, Advanced Tumor Cell Specific Promoters: Up-regulating hTERT & hAFP Activities, American Society of Gene Therapy, 2003
Posters & Platform Presentations
Jang Y, Cho H, Chun J, Park K, Nowakowska A, Kim J, Lee H, Lee C, Han Y, Lee HJ, Shin HY, Kim YB, Baculoviral COVID-19 Delta DNA vaccine cross-protects against SARS-CoV2 variants in K18-ACE2 transgenic mice, Vaccine, 2022, 41:1223
Kim U, Kim S, Kim N, Shin HY, Mammary-Enriched Transcription Factors Synergize to Activate the Wap Super-Enhancer for Mammary Gland Development, Int J Mol Sci, 2022, 23:11680
Kim S, Shin HY, Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases, Int J Mol Sci, 2022, 23:11297
Kim S, Shin HY, Understanding the Tissue Specificity of ZIKV Infection in Various Animal Models for Vaccine Development, Vaccines, 2022, 10:1517
Kim S, Nowakowska A, Kim YB, Shin HY, Integrated CRISPR-Cas9 System-Mediated Knockout of IFN-γ and IFN-γ Receptor 1 in the Vero Cell Line Promotes Viral Susceptibility, Int J Mol Sci, 2022, 23:8217
Choi MK, Kim J, Park HM, Lim CM, Pham TH, Shin HY, Kim SE, Oh DK, Yoon DY, The DPA-derivative 11S, 17S-dihydroxy 7,9,13,15,19 (Z,E,Z,E,Z)-docosapentaenoic acid inhibits IL-6 production by inhibiting ROS production and ERK/NF-κB pathway in keratinocytes HaCaT stimulated with a fine dust PM10, Ecotoxicol Environ Saf, 2022, 232:113252